Trulicity patient holding the Trulicity Pen

Trulicity can help lower your A1C

Along with diet and exercise

What is Trulicity

May start lowering blood sugar from the first dose

Lowers the risk of cardiovascular events, such as heart attack, stroke, & death^*

Not insulin

Taken once weekly

You may lose a little weight^†

^*In people with type 2 diabetes with known heart disease or multiple risk factors.
^†In studies with other diabetes medications weight change in adults ranged from +0.4 lbs (.75 mg) to −10.1 lbs (4.5 mg). Trulicity is not a weight loss drug. Individual results may vary.

Trulicity helps activate your body to release its own insulin, like it's supposed to.

Once-weekly Trulicity helps control blood sugar in 3 ways

How Trulicity works in your body

It can limit how much sugar gets into your blood from your liver
It helps slow down how quickly food leaves your stomach
It helps your pancreas release insulin in response to high levels of sugar in your blood after you eat

Trulicity may fit into your busy life

Once-weekly Trulicity can be taken

Any time of the day

With or without food

And works 24/7

If traveling, Trulicity can be stored at room temperature for up to 14 days

Trulicity being put in a backpack

The easy-to-use^‡ Trulicity pen makes taking your Trulicity dose simple.

94% of people who used the Trulicity Pen found it easy to use

^‡In a study, 94% of people who used the Trulicity Pen found it easy to use.

Read the Instructions for Use included with your pen.

Single-dose pen

Don’t have to see or handle a needle

Works with a click of a button

Trulicity Support

Trulicity support

The Trulicity team can offer you personalized assistance in your treatment journey. That means support and resources for what you need to know—when you need to know it.

PURPOSE AND SAFETY SUMMARY WITH WARNINGS

Important Facts About Trulicity^® (Trῡ-li-si-tee). It is also known as dulaglutide.

Trulicity is a prescription medicine for adults with type 2 diabetes used to improve blood sugar (glucose) and used to reduce the risk of major cardiovascular events ( problems having to do with the heart and blood vessels) such as death, heart attack, or stroke in people who have heart disease or multiple cardiovascular risk factors.

Trulicity is given through an injection (needle). You take it once a week by injecting it under the skin of your stomach, thigh, or upper arm. Use Trulicity together with the diet and exercise that your doctor recommends.

Warnings

Trulicity may cause tumors in the thyroid, including thyroid cancer. Watch for possible symptoms, such as a lump or swelling in the neck, trouble swallowing, hoarseness, or shortness of breath. If you have a symptom, tell your doctor.

Do not use Trulicity if you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC).
Do not use Trulicity if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
Do not use Trulicity if you are allergic to dulaglutide or other ingredients in Trulicity.

Ask your doctor how to recognize the serious side effects below and what to do if you think you have one:

Inflamed pancreas (pancreatitis). Stop using Trulicity and call your healthcare provider right away if you have severe pain in your stomach area (abdomen), with or without vomiting, that will not go away. You may feel the pain from your abdomen to your back.

Changes in vision. Tell your healthcare provider if you have changes in your eyesight (vision) during treatment with Trulicity.

Low blood sugar (hypoglycemia). Signs and symptoms of low blood sugar may include dizziness or light-headedness, confusion or drowsiness, headache, blurred vision, slurred speech, fast heartbeat, sweating, hunger, shakiness, feeling jittery, weakness, anxiety, irritability, or mood changes.

Serious allergic reactions. Stop using Trulicity and get medical help right away if you have any symptoms of a serious allergic reaction which may include: swelling of your face, lips, tongue or throat, problems breathing or swallowing, severe rash or itching, fainting or feeling dizzy, or very rapid heartbeat.

Acute kidney injury. In people who have kidney problems, diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration). This may cause kidney problems to get worse.

Severe stomach problems. Trulicity may cause stomach problems, which could be severe.

Common side effects

The most common side effects of Trulicity include nausea, diarrhea, vomiting, abdominal pain and decreased appetite, indigestion, and fatigue.

These are not all the possible side effects of Trulicity.

Tell your doctor if you have any side effects. You can report side effects at 1-800-FDA-1088 or www.fda.gov/medwatch.

Before using

Your healthcare provider should show you how to use Trulicity before you use it for the first time.
Before you use Trulicity, talk to your doctor about low blood sugar and how to manage it.

Review these questions with your doctor:

Do you have other medical conditions, including problems with your pancreas, kidneys, liver, or stomach, or have a history of diabetic retinopathy (vision problems related to diabetes)?
Do you take other diabetes medicines, such as insulin or sulfonylureas?
Do you take any other prescription medicines or over-the-counter drugs, vitamins, or herbs?

Review the list below with your doctor. Trulicity may not be right for you if:

You are pregnant or plan to become pregnant or breastfeeding or plan to breastfeed.
You have type 1 diabetes.
You have or have had an inflamed pancreas (pancreatitis).
You have severe intestinal or stomach problems, such as slowed emptying or problems with digesting food.
You are a child under 18 years old.

How to take

Read the Instructions for Use that come with Trulicity.
Use Trulicity exactly as your doctor says.
Do not share your Trulicity pen, syringe, or needles with another person.
Do not give Trulicity to other people.
If you take too much Trulicity, call your healthcare provider or seek medical advice promptly.

Learn more

For more information, call 1-844-TRU-INFO (1-844-878-4636).

This summary provides basic information about Trulicity but does not include all information known about this medicine. Read the information that comes with your prescription each time your prescription is filled. This information does not take the place of talking with your doctor. Be sure to talk to your doctor or other healthcare provider about Trulicity and how to take it. Your doctor is the best person to help you decide if Trulicity is right for you.

Trulicity^® and its delivery device base are registered trademarks owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates.

DG CON HL BS SEP 2020