Trulicity patient at her dinner table eating a balanced meal.

How to Use Trulicity

Whether you are new to Trulicity, or about to transition to a different dose, the information on this site can help you get started.

What do you need to know to get started?

How to save

The benefits of Trulicity

How to take Trulicity

Getting access to savings

You may be eligible to pay as little as $25 for 12 Trulicity pens with the Trulicity Savings Card.

^†Offer good for up to 12 months of Trulicity. Patients must have coverage for Trulicity through their commercial drug insurance to pay as little as $25 for up to 12 pens of Trulicity. Offer subject to a monthly cap of $150 and a separate annual cap of $1800. Patient is responsible for any applicable taxes, fees, or amounts exceeding monthly or annual caps. This offer is invalid for Patients without commercial drug insurance or whose prescription claims for Trulicity are eligible to be reimbursed, in whole or in part, by any governmental program, including, without limitation, Medicaid, Medicare, Medicare Part D, Medigap, DoD, VA, TRICARE^®/CHAMPUS, or any State Patient or Pharmaceutical Assistance Program. Offer void where prohibited by law and subject to change or discontinue without notice. Card activation is required. Subject to additional terms and conditions, which can be found here.

How Trulicity can help adults with type 2 diabetes^*

^*Along with diet and exercise.

Male Trulicity patient holding the Trulicity Pen

A1C reduction
Trulicity may offer lasting A1C improvements. In a study, some Trulicity users saw a significant improvement when their A1C was measured after 6 months, and it was still improved after they had been taking Trulicity for 1 year.

The majority of people reached an A1C under 7%
In Trulicity studies with other medication, 50% to 67% of patients with an average starting A1C of 8% to 8.6% reached an A1C < 7% across 4 doses.

Starts acting from the first dose
Trulicity is a non-insulin option that helps your body release the insulin it's already making.

People lost up to 10 lbs
Trulicity is not a weight loss drug. In studies with other diabetes medications, weight change in adults ranged from +0.4 lbs (0.75 mg) to −10.1 lbs (4.5 mg). Individual results may vary.

Select Important Safety Information:

Ask your doctor how to recognize possible serious side effects and what to do.
Low blood sugar (hypoglycemia). Your risk for getting low blood sugar may be higher if you use Trulicity with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin. Signs and symptoms of low blood sugar may include dizziness or light-headedness, confusion or drowsiness, headache, blurred vision, slurred speech, fast heartbeat, sweating, hunger, shakiness, feeling jittery, weakness, anxiety, irritability, or mood changes.

Select Important Safety Information:

Serious allergic reactions. Stop using Trulicity and get medical help right away if you have any symptoms of a serious allergic reaction which may include: swelling of your face, lips, tongue or throat, problems breathing or swallowing, severe rash or itching, fainting or feeling dizzy, or a very rapid heartbeat.

Choosing your Trulicity day

Trulicity is designed to fit into your busy life. Trulicity is taken once a week. On your Trulicity day, you can take your dose at any time of the day, with or without food. So start by picking the best day for you and mark it as your Trulicity day. Do your best to stick to the same day every week.

If you missed your Trulicity dose, or need to change your Trulicity day, read below.

If you'd like to change your Trulicity day, you can. If it's been more than 3 days since your last dose, you can switch. If it's been fewer than 3 days since your last dose, wait until the following week to take the dose on your new Trulicity day.^‡

^‡ Do not take 2 doses of Trulicity within 3 days of each other.

The doctor just told me to read the instructions because she said it was easy to use^*. So, I took her word, and she was right, it is easy to use^* Trulicity.

- Cesar

Real Trulicity User

Using your Trulicity Pen

Read the Instructions for Use included with your pen.

Every dose of Trulicity comes in the easy-to-use^* pen, so you can continue to have the same experience with once-weekly Trulicity, regardless of the dose you've been prescribed.

^*In a study, 94% of people who used the Trulicity Pen found it easy to use.

Uncap the pen

Step 2: Pack and Unlock the Trulicity Pen

Place and unlock

Press and hold

Choosing your injection site

Your doctor can help you choose the areas on your body that are best to use Trulicity. Be sure to use a different spot in that area every time. Suggested areas to use Trulicity are your upper arm, abdomen, or thigh (see diagram).

More dose options. More treatment possibilities.

Trulicity has 4 dose options to better fit your diabetes needs. And because each dose comes in the easy-to-use^* pen, you can continue to have the same experience with once-weekly Trulicity, regardless of the dose you've been prescribed.

^*In a study, 94% of people said it was easy to use. Read the Instructions for Use included with your pen.

What side effects might occur when starting Trulicity?

Managing side effects →

SAFETY SUMMARY WITH WARNINGS

Warnings:

Trulicity may cause tumors in the thyroid, including thyroid cancer. Watch for possible symptoms, such as a lump or swelling in the neck, trouble swallowing, hoarseness, or shortness of breath. If you have a symptom, tell your doctor.

Do not use Trulicity if you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC).
Do not use Trulicity if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
Do not use Trulicity if you are allergic to dulaglutide or other ingredients in Trulicity.

Ask your doctor how to recognize the serious side effects below and what to do if you think you have one:

Inflamed pancreas (pancreatitis). Stop using Trulicity and call your healthcare provider right away if you have severe pain in your stomach area (abdomen), with or without vomiting, that will not go away. You may feel the pain from your abdomen to your back.
Low blood sugar (hypoglycemia). Your risk for getting low blood sugar may be higher if you use TRULICITY with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin.
Signs and symptoms of low blood sugar may include dizziness or light-headedness, confusion or drowsiness, headache, blurred vision, slurred speech, fast heartbeat, sweating, hunger, shakiness, feeling jittery, weakness, anxiety, irritability, or mood changes.
Serious allergic reactions. Stop using Trulicity and get medical help right away if you have any symptoms of a serious allergic reaction which may include swelling of your face, lips, tongue or throat, problems breathing or swallowing, severe rash or itching, fainting, or feeling dizzy, or very rapid heartbeat.
Acute kidney injury. In people who have kidney problems, diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration). This may cause kidney problems to get worse.
Severe stomach problems. Trulicity may cause stomach problems, which could be severe.
Changes in vision. Tell your healthcare provider if you have changes in your eyesight (vision) during treatment with Trulicity.
Gallbladder problems. Gallbladder problems have happened in some people who take TRULICITY. Tell your healthcare provider right away if you get symptoms of gallbladder problems, which may include pain in your upper stomach (abdomen), fever, yellowing of skin or eyes (jaundice), clay-colored stools.

Common side effects

The most common side effects of Trulicity include nausea, diarrhea, vomiting, abdominal pain and decreased appetite, indigestion, and fatigue.

These are not all the possible side effects of Trulicity

Tell your doctor if you have any side effects. You can report side effects at 1-800-FDA-1088 or www.fda.gov/medwatch .

Before using

Your healthcare provider should show you how to use Trulicity before you use it for the first time.
Before you use Trulicity, talk to your doctor about low blood sugar and how to manage it.

Review these questions with your doctor:

Do you have other medical conditions, including problems with your pancreas, kidneys, liver, or stomach, or have a history of diabetic retinopathy (vision problems related to diabetes)?
Do you take other diabetes medicines, such as insulin or sulfonylureas?
Are you pregnant or plan to become pregnant or breastfeeding or plan to breastfeed?
Do you take any other prescription medicines or over-the-counter drugs, vitamins, or herbs?

How to take

Read the Instructions for Use that come with Trulicity.
Use Trulicity exactly as your doctor says.
Do not share your Trulicity pen, syringe, or needles with another person.
Do not give Trulicity to other people.
If you take too much Trulicity, call your healthcare provider or seek medical advice promptly.

Learn more

Trulicity is a prescription medicine. For more information, call 1-844-TRU-INFO (1-844-878-4636).

This summary provides basic information about Trulicity but does not include all information known about this medicine. Read the information that comes with your prescription each time your prescription is filled. This information does not take the place of talking with your doctor. Be sure to talk to your doctor or other healthcare provider about Trulicity and how to take it. Your doctor is the best person to help you decide if Trulicity is right for you.

DG CON HL BS 14SEP2022

Trulicity^® and its delivery device base are registered trademarks owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates.

INDICATIONS

Trulicity^® (Tro-li-si-tee) is for adults with type 2 diabetes used along with diet and exercise to improve blood sugar (glucose). Trulicity is also used in adults with type 2 diabetes to reduce the risk of major cardiovascular events (problems having to do with the heart and blood vessels) such as death, heart attack, or stroke in people who have heart disease or multiple cardiovascular risk factors.

It is not known if TRULICITY can be used in people who have had inflammation of the pancreas (pancreatitis). TRULICITY is not for use in people with type 1 diabetes and is not recommended for use in people with severe stomach or intestinal problems. It is not known if TRULICITY is safe and effective for use in children. TRULICITY should not be used in children under 18 years of age.
Trulicity is given through an injection (needle). You take it once a week by injecting it under the skin of your stomach, thigh, or upper arm.