What are some factors contribute to cardiovascular disease (CVD)?

Smoking, High blood pressure, high cholesterol, obesity and family history.

How can I manage my cardiovascular (CV) risk?

With Trulicity, you may improve your blood sugar and A1C, and you may also reduce your risk of heart attack, stroke, or death. Ask your doctor about your CV risk and how Trulicity may be able to help.

Your blood sugar goals may be within reach

Q: Am I at cardiovascular (CV) risk?

Whether or not you have already experienced a heart attack or stroke, when you have type 2 diabetes you are more likely to develop heart disease, also known as cardiovascular disease (CVD), than people without type 2 diabetes.

In adults with type 2 diabetes once-weekly Trulicity lowers blood sugar by helping your body release the insulin it's already making. It starts working from the first dose, and seeing the impact of one change can motivate you to make more of them.

Get to know Trulicity

About type 2 diabetes

You are not alone. Millions of people are living with diabetes and going through some of the same things you are.

Diabetes can be hard to manage. It’s important to remember that diabetes is a progressive disease, which means it usually changes over time. And when it changes, your doctor might have to change your treatment as well.

What happens in your body

When you have type 2 diabetes, your body has trouble using or making enough insulin. Insulin is a hormone that helps the sugar from your food enter your cells. It’s something everyone needs and, for most people, the body naturally makes enough. But if you have type 2 diabetes, your body might not use the insulin you make efficiently. Sugar (or glucose) cannot enter the cells to be used for energy. Instead, it builds up in your bloodstream, causing high blood sugar.

Symptoms of high blood sugar can include:

feeling extraordinarily hungry or thirsty
feeling extraordinarily tired
experiencing blurred vision
frequently needing to urinate

If your blood sugar isn’t where it needs to be, Trulicity may help. Trulicity helps your body do what it’s supposed to do—release its own insulin. This may help lower your blood sugar. Ask your doctor if once-weekly Trulicity is right for you during your next visit.

Diabetes and cardiovascular risk

Whether or not you've already experienced a heart attack or stroke, when you have type 2 diabetes you are more likely to develop heart disease, also known as cardiovascular disease (CVD), than people without type 2 diabetes.

Factors that can contribute to CVD

Smoking

High Blood Pressure

High Cholesterol

Obesity

Family History

Trulicity lowers the risk of cardiovascular events such as heart attack stroke and death*

How can Trulicity help reduce my risk of CV events?

For adults with type 2 diabetes, with Trulicity you may improve your blood sugar and A1C, and you may also reduce your risk of CV events like heart attack, stroke or death.

Ask your doctor about your risk of CV events and how Trulicity may be able to help.

CV = cardiovascular.

Indication:

Trulicity is used in adults with type 2 diabetes to reduce the risk of major cardiovascular events (problems having to do with the heart and blood vessels) such as death, heart attack, or stroke in people who have heart disease or multiple cardiovascular risk factors.

Select Important Safety Information:

Ask your healthcare provider how to recognize possible serious side effects and what to do.

Severe stomach problems. Trulicity may cause stomach problems, which could be severe.

See what Trulicity can do for adults with type 2 diabetes

What is Trulicity?

SAFETY SUMMARY WITH WARNINGS

Warnings:

Trulicity may cause tumors in the thyroid, including thyroid cancer. Watch for possible symptoms, such as a lump or swelling in the neck, trouble swallowing, hoarseness, or shortness of breath. If you have any of these symptoms, tell your healthcare provider.

Do not use Trulicity if you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC).
Do not use Trulicity if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
Do not use Trulicity if you are allergic to dulaglutide or other ingredients in Trulicity.

Ask your healthcare provider how to recognize possible serious side effects and what to do :

Inflamed pancreas (pancreatitis). Stop using Trulicity and call your healthcare provider right away if you have severe pain in your stomach area (abdomen), with or without vomiting, that will not go away. You may feel the pain from your abdomen to your back.
Low blood sugar (hypoglycemia). Your risk for getting low blood sugar may be higher if you use TRULICITY with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin.
Signs and symptoms of low blood sugar may include dizziness or light-headedness, confusion or drowsiness, headache, blurred vision, slurred speech, fast heartbeat, sweating, hunger, shakiness, feeling jittery, weakness, anxiety, irritability, or mood changes.
Serious allergic reactions. Stop using Trulicity and get medical help right away if you have any symptoms of a serious allergic reaction which may include swelling of your face, lips, tongue or throat, problems breathing or swallowing, severe rash or itching, fainting, or feeling dizzy, or very rapid heartbeat.
Acute kidney injury. In people who have kidney problems, diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration). This may cause kidney problems to get worse.
Severe stomach problems. Trulicity may cause stomach problems, which could be severe.
Changes in vision. Tell your healthcare provider if you have changes in your eyesight (vision) during treatment with Trulicity.
Gallbladder problems. Gallbladder problems have happened in some people who take Trulicity. Tell your healthcare provider right away if you get symptoms of gallbladder problems, which may include pain in your upper stomach (abdomen), fever, yellowing of skin or eyes (jaundice), clay-colored stools.

Common side effects

The most common side effects of Trulicity include nausea, diarrhea, vomiting, abdominal pain and decreased appetite, indigestion, and fatigue.

These are not all the possible side effects of Trulicity.

Tell your healthcare provider if you have any side effects. You can report side effects at 1-800-FDA-1088 or www.fda.gov/medwatch .

Before using

Your healthcare provider should show you how to use Trulicity before you use it for the first time.
Before you use Trulicity, talk to your healthcare provider about low blood sugar and how to manage it.

Review these questions with your healthcare provider:

Do you have other medical conditions, including problems with your pancreas, kidneys, liver, or stomach, or have a history of diabetic retinopathy (vision problems related to diabetes)?
Do you take other diabetes medicines, such as insulin or sulfonylureas?
Are you pregnant or plan to become pregnant or breastfeeding or plan to breastfeed?
Do you take any other prescription medicines or over-the-counter drugs, vitamins, or herbal supplements?

How to take

Read the Instructions for Use that come with Trulicity.
Use Trulicity exactly as your healthcare provider says.
Do not share your Trulicity pen, syringe, or needles with another person.
Do not give Trulicity to other people.
If you take too much Trulicity, call your healthcare provider or seek medical advice promptly.

Learn more

Trulicity is a prescription medicine. For more information, call 1-844-TRU-INFO (1-844-878-4636) or go to www.TRULICITY.com.

This summary provides basic information about Trulicity but does not include all information known about this medicine. Read the information that comes with your prescription each time your prescription is filled. This information does not take the place of talking with your healthcare provider. Be sure to talk to your healthcare provider about Trulicity and how to take it. Your healthcare provider is the best person to help you decide if Trulicity is right for you.

DG CON HL BS 17NOV2022

Trulicity^® and its delivery device base are registered trademarks owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates.

INDICATIONS

Trulicity^® (Trῡ-li-si-tee) is for adults and children 10 years of age and older with type 2 diabetes used along with diet and exercise to improve blood sugar (glucose). Trulicity is also used in adults with type 2 diabetes to reduce the risk of major cardiovascular events (problems having to do with the heart and blood vessels) such as death, heart attack, or stroke in people who have heart disease or multiple cardiovascular risk factors.

It is not known if TRULICITY can be used in people who have had inflammation of the pancreas (pancreatitis). TRULICITY is not for use in people with type 1 diabetes and is not recommended for use in people with severe stomach or intestinal problems. It is not known if TRULICITY is safe and effective in children under 10 years of age.
Trulicity is given through an injection (needle). You take it once a week by injecting it under the skin of your stomach, thigh, or upper arm.