What is Trulicity?
Trulicity is not an insulin. It's a kind of medicine called a glucagon-like peptide-1 receptor agonist (GLP-1 RA). It works like the GLP-1 hormone in your body. The body naturally releases GLP-1 after you eat to help control blood sugar. Trulicity helps your pancreas release insulin when your blood sugar is high. It can also limit how much sugar goes into your blood from your liver, and it slows the emptying of food from your stomach.
Trulicity is taken once a week and works 24/7, responding when your blood sugar rises. Plus, Trulicity comes in an easy-to-use* pen that’s activated with the click of a button. Trulicity pens come in 2 doses—one with a yellow label (0.75 mg), the other with a blue label (1.5 mg). Your healthcare provider will tell you which is right for you.
*In a study, 94% of people who used the Trulicity pen found it easy to use. Before starting Trulicity, your healthcare provider should show you how to use the pen.
Select Safety Information
Do not take Trulicity if:
- you or any of your family members have ever had Medullary Thyroid Carcinoma (MTC)
- you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
- you have had an allergic reaction to dulaglutide or any of the other ingredients in Trulicity
If you have symptoms of a serious allergic reaction while taking Trulicity, such as itching, rash, or difficulty breathing, stop taking Trulicity and get medical help right away.
How Trulicity can help
Trulicity can help improve your numbers
Trulicity, along with diet and exercise, may help lower your blood sugar and A1C. In a study, the higher dose helped 78% of people and the lower dose helped 66% of people get to the A1C goal of below 7%.
Select Safety Information
Trulicity may cause serious side effects, including inflammation of your pancreas (pancreatitis). If you have pain in your stomach area (abdomen) that is severe and will not go away, stop taking Trulicity and call your healthcare provider right away. The pain may happen with or without vomiting. It may be felt going from your abdomen through to your back. This may be a symptom of inflammation of your pancreas (pancreatitis).
Trulicity may offer lasting A1C improvements
In a study, some Trulicity users saw a significant improvement when their A1C was measured after 6 months, and it was still improved after they had been taking Trulicity for 1 year.
Trulicity is designed to be taken once a week, which may help you fit it into your busy life. You can take Trulicity any time of day, with or without meals. Just pick which day of the week will be your Trulicity Day and remember to keep taking it that day, every week. It works in your body all week, helping you get better A1C and blood sugar numbers. To get started and pick your Trulicity Day, click here.
The pen was designed with patients in mind
Trulicity comes in an easy-to-use pen that’s activated with the click of a button (in a study, 94% of people said it was easy to use). There’s no need to mix anything or dial a dose. And it has a pre-attached, hidden needle that you don’t need to see or handle.Watch how to use the Trulicity pen
What to expect when you take Trulicity
If you monitor your blood sugar levels, you may see a reduction in your numbers. In some studies, most people taking Trulicity noted better blood sugar numbers before eating in the morning (fasting blood sugar). Next time you visit your healthcare provider, your A1C numbers might be better, too. After 6 months, you may see significant improvements in your A1C. If you do not reach your A1C goal after taking Trulicity for 6 months, talk to your healthcare provider about adjusting your medications, diet, and/or exercise routine.
Trulicity is not a weight loss drug, but some people may lose a little weight. In a study, many people lost a little weight over the course of 6 months and then kept it off during the rest of the study. Of people who lost weight in clinical trials, the average weight loss was 2 pounds to 6 pounds. While many people in clinical trials lost weight, some did gain weight.
Possible side effects
When you start taking Trulicity, you may experience some side effects. The most common side effects with Trulicity tend to be mild to moderate. These may include nausea, diarrhea, vomiting, abdominal pain, decreased appetite, and indigestion. In studies, some people (8%-29%) using Trulicity experienced nausea.
In studies, gastrointestinal side effects were more common in people taking Trulicity than people taking placebo, and people taking Trulicity were more likely to stop treatment because of these side effects.
Trulicity may also cause serious side effects, including possible thyroid tumors (including cancer), inflammation of your pancreas, low blood sugar, serious allergic reactions, or severe stomach problems. In people who have kidney problems, side effects such as nausea, vomiting, and diarrhea may cause a loss of fluids (dehydration), which may cause kidney problems to get worse (including kidney failure).
If you experience side effects, talk with your healthcare provider.
Ways to manage nausea
If you experience nausea, talk with your healthcare provider. In the meantime, here are some things that may help:
- Eat smaller meals
- Stop eating when you feel full
- Avoid fried or other fatty foods
- Try foods or drinks containing ginger
We’re here to help
If you have questions about what to expect with Trulicity, we’re here to help. Call The Lilly Answers Center at 1-844-TRU-INFO (1-844-878-4636). We won't be able to replace the advice of your healthcare provider, but we'll do our very best to help you.